T?tigkeitsbereiche

LEHRGEBIETE

• Anorganische Chemie
• Biologische Chemie
• Biotechnologie
• Umweltchemie

FORSCHUNGSBEREICHE

• Koordinationschemie
• Bioanorganische Chemie
• Bioorganische Chemie
• Bionanochemie

Publikationen

Ausgew?hlte Publikationen und Referenzen

Publikationen
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Ausgew?hlte Publikationen

• Dimitri? Markovi?, J., Dimi?, D., Eichhorn, T., Milenkovi?, D., Pavi?evi?, A., ?iki?, D., ?ivkovi?, E., ?oki?, V., Rüffer, T., Kalu?erovi?, G.N. (2025): Ru(II) Complexes with 3,4-Dimethylphenylhydrazine: Exploring In Vitro Anticancer Activity and Protein Affinities Biomolecules 15, 350. doi.org/10.3390/biom15030350
• Kasalovi?, M.P., Dimi?, D., Jela?a, S., Maksimovi?-Ivani?, D., Mijatovi?, S., Zmejkovski, B.B., Schreiner, S.H.F., Rüffer, T., Panteli?, N.?., Kalu?erovi?, G.N. (2024) Trimethyltin(IV) Bearing 3-(4-Methyl-2-oxoquinolin-1(2H)-yl)propanoate Causes Lipid Peroxidation-Mediated Autophagic Cell Death in Human Melanoma A375 Cells, Pharmaceuticals 17, 372.
• Ludwig, G., Ran?elovi?, I., Dimi?, D., Komazec, T., Maksimovi?-Ivani?, D., Mijatovi?, S., Rüffer, T., Kalu?erovi?, G.N. (Pentamethylcyclopentadienyl)chloridoiridium(III) Complex Bearing Bidentate Ph₂PCH₂CH₂SPh-κP,κS Ligand, Biomolecules 14, 420.
• Eichhorn, T., Kolbe, F., Mi?i?, S., Dimi?, D., Morgan, I., Saoud, M., Milenkovi?, D., Markovi?, Z., Rüffer, T., Dimitri? Markovi?, J., Kalu?erovi?, G.N. (2023): Synthesis, Crystallographic Structure, Theoretical Analysis, Molecular Docking Studies, and Biological Activity Evaluation of Binuclear Ru (II)-1-Naphthylhydrazine Complex, Int. J. Mol. Sci., 24, 689.
• Predarska, I., Saoud, M., Dra?a, D., Morgan, I., Komazec, T., Eichhorn, T., Mihajlovi?, E., Dun?erovi?, D., Mijatovi?, S., Maksimovi?-Ivani?, D., Hey-Hawkins, E., Kalu?erovi?, G.N. (2022): Mesoporous Silica Nanoparticles Enhance the Anticancer Efficacy of Platinum (IV)-Phenolate Conjugates in Breast Cancer Cell Lines, Nanomaterials, 12, 3767.
• Kne?evi?, N.?., Ili?, N., Kalu?erovi?, G.N. (2022): Mesoporous Silica Nanoparticles for pH-Responsive Delivery of Iridium Metallotherapeutics and Treatment of Glioblastoma Multiforme, Inorganics 10, 250.
• Bensing, C., Moji?, M., Bulatovi?, M., Edeler, D., Pérez-Quintanilla, D., Gómez-Ruiz, S., Maksimovi?-Ivani?, D., Mijatovi?, S., Kalu?erovi?, G.N. (2022): Effect of chain length on the cytotoxic activity of (alkyl-ω-ol) triphenyltin (IV) loaded into SBA-15 nanostructured silica and in vivo study of SBA-15~Cl| Ph₃Sn(CH₂)₈OH, Biomat. Adv. 140, 213054.
• Dra?a, D., Edeler, D., Saoud, M., Doj?inovi?, B.,? Dun?erovi?, D., ?mura, G., Maksimovi?-Ivani?, D., Mijatovi?, S., Kalu?erovi?, G.N. (2021): Antitumor potential of cisplatin loaded into SBA-15 mesoporous silica nanoparticles against B16F1 melanoma cells: in vitro and in vivo studies, J. Inorg. Biochem. 217, 111383
• Arlt, S., Petkovi?, V., Ludwig, G., Eichhorn, T., Lang, H., Rüffer, T., Mijatovi?, S., Maksimovi?-Ivani?, D., Kalu?erovi?, G.N. (2021): Arene Ruthenium(II) Complexes Bearing the κ-P or κ-P,κ-S Ph₂P(CH₂)₃SPh Ligand. Molecules 26, 1860.
• J?nicke, P., Lennicke, C., Meister, A., Seliger, B., Wessjohanna, L.A., Kalu?erovi?, G.N. (2021): Fluorescent spherical mesoporous silica nanoparticles loaded with emodin: Synthesis, cellular uptake and anticancer activity, Mat. Sci. Eng. C 119, 111619
• Smolko, L., Smolková, R., Samo?ová, E., Morgan, I., Saoud, M., Kalu?erovi?, G.N. (2020): Two isostructural Co(II) flufenamato and niflumato complexes with bathocuproine: analogues with a different cytotoxic activity, J. Inorg. Biochem. 210, 111160.
• Edeler, D., Dra?a, D., Petkovi?, V., Natalio, F., Maksimovi?-Ivani?, D., Mijatovi?, S., Schmidt, H., Kalu?erovi?, G.N. (2019):? Impact of the mesoporous silica SBA-15 functionalization on the mode of action of Ph₃Sn(CH₂)₆OH,? Mat. Sci. Eng. C 100, 315-322.
• Edeler D, Arlt S, Petkovi? V, Ludwig G, Dra?a D, Maksimovi?-Ivani? D, Mijatovi? S, Kalu?erovi? GN. (2018), Drug delivery system for emodin based on mesoporous silica SBA-15 mesoporous silica: Preparation, characterization and in vitro study, J Inorg Biochem. 180, 155–162.
• Krajnovi? T., Maksimovi?-Ivani? D., Mijatovi? S., Dra?a D., Wolf K., Edeler D., Wessjohann L.A., Kalu?erovi? G.N. (2018), Drug Delivery System for Emodin Based on Mesoporous Silica SBA-15, Nanomaterials 8, pii: E322
• Hübner, D., Kalu?erovi?, M.R., Gómez-Ruiz, S. and Kalu?erovi?, G.N. (2017), Anionic chlorido(triphenyl)tin(IV) bearing N-phthaloylglycinato or 1,2,4-benzenetricarboxylato 1,2-anhydride ligands: potential cytotoxic and apoptosis-inducing agents against several types of cancer, Chem. Biol. Drug Des. 89, 628–633.
• Kalu?erovi?, G.N., Abbas, M., Kautz, H.C., Wadaan, M.A.M., Lennicke, C., Seliger, B. and Wessjohann, L.A. (2017), Methionine and seleno-methionine type peptide and peptoid building blocks synthesized by five-component five-center reactions, Chem. Commun. 53, 3777–3780.
• Ludwig, G., Moji?, M., Bulatovi?, M.Z., Mijatovi?, S., Maksimovi?-Ivani?, D., Steinborn, D. and Kalu?erovi?, G.N. (2016). Biological Potential of Halfsandwich Ruthenium(II) and Iridium(III) Complexes. Anticancer Agents Med Chem. 16, 1455–1460.
• Bensing, C., Moji?, M., Gómez-Ruiz, S., Carralero, S., Doj?inovi?, B., Maksimovi?-Ivani?, D., Mijatovi?, S. and Kalu?erovi? G.N. (2016): Evaluation of functionalized mesoporous silica SBA-15 as a carrier system for Ph3Sn(CH2)3OH against A2780 ovarian carcinoma cell line, Dalton Trans. 45, 18984–18993.
• Edeler, D., Kalu?erovi?, M.R., Doj?inovi?, B., Schmidt, H. and Kalu?erovi? G.N. (2016): SBA-15 mesoporous silica particles loaded with cisplatin induce senescence in B16F10 cells, RSC Advances. 6, 111031–111040.
• Kalu?erovi?, G. N., Krajnovi?, T., Momcilovic, M., Stosic-Grujicic, S., Mijatovi?, S., Maksimovi?-Ivani?, D., Hey-Hawkins, E. (2015). Ruthenium(II) p-cymene complex bearing 2,2’-dipyridylamine targets caspase 3 deficient MCF-7 breast cancer cells without disruption of antitumor immune response, J. Inorg. Biochem. 153, 315–321.
• Bulatovi?, M. Z., Maksimovi?-Ivani?, D., Bensing, C., Gómez-Ruiz, S., Steinborn, D., Schmidt, H., Moji?, M., Kora?, A., Goli?, I., Pérez-Quintanilla, D., Mom?ilovi?, M., Mijatovi?, S. and Kalu?erovi?, G. N. (2014). Organotin(IV)-Loaded Mesoporous Silica as a Biocompatible Strategy in Cancer Treatment, Angew. Chem. Int. Ed. 53, 5982–5987; Angew. Chem. 126, 6092–6097.
• Panteli?, N., Zmejkovski, B.B., Trifunovi?-Macedoljan, J., Savi?, A., Stankovi?, D., Damjanovi?, A., Jurani?, Z., Kalu?erovi?, G. N. and Sabo, T. J. (2013). Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate, J. Inorg. Biochem. 128C, 146–153.
• Ludwig, G., Mijatovi?, S., Ran?elovi?, I., Bulatovi?, M., Miljkovi?, D., Maksimovi?-Ivani?, D., Korb, M., Lang, H., Steinborn, D. and Kalu?erovi?, G. N. (2013). Biological activity of neutral and cationic iridium(III) complexes with κP and κP,κS coordinated Ph2PCH2S(O)xPh (x = 0–2) ligands, Europ. J. Med. Chem. 69C, 216–222.
• Maksimovi?-Ivani?, D., Mijatovi?, S., Mirkov, I, Sto?i?-Gruji?i?, S.D., Miljkovi?, D., Sabo, T.J., Trajkovi?, V. and Kalu?erovi?, G.N. (2012). Melanoma tumor inhibition by tetrachlorido(O,O’-dibutyl-ethylenediamine-N,N’-di-3-propionate)platinum(IV) complex: in vitro and in vivo investigations, Metallomics 4, 1155–1159.
• Sanchez-Munoz, S., Gómez-Ruiz, S., Perez-Quintanilla, D., Morante-Zarcero, S., Sierra, I., Prashar, S., Paschke, R. and Kalu?erovi?, G.N. (2012). Preliminary study of the anticancer applications of mesoporous materials functionalized with the natural product betulinic acid; ChemMedChem, 7, 670–679.
• Kalu?erovi?, G.N., Dietrich, A., Kommera, H., Kuntsche, J., M?der, K., Mueller, T. and Paschke, R. (2012). Liposomes as vehicles for water insoluble platinum-based potential drug: 2-(4-(tetrahydro-2H-pyran-2-yloxy)-undecyl)propane-1,3-diamminedichloro-platinum(II), Europ. J. Med. Chem. 54, 567–572.
• Gómez-Ruiz, S., Ceballos-Torres, J., Prashar, S., Fajardo, M., ?i?ak, ?,. Jurani?, Z. D. and Kalu?erovi?, G. N. (2011). One ligand different metal complexes: Biological studies of titanium(IV), tin(IV) and gallium(III) derivatives with the 2,6-dimethoxypyridine-3-carboxylato ligand, J. Organomet. Chem. 696, 3206–3213.
• Kalu?erovi?, G. N., Pérez-Quintanilla, D., Sierra, I., Prashar, S., Hierro, I., ?i?ak, ?., Jurani?, Z. D., Fajardo, M. and and Gómez-Ruiz, S. (2010). Study of the influence of the metal complex on the cytotoxic activity of titanocene-functionalized mesoporous materials. J. Mater. Chem. 20, 806–814.
• Kalu?erovi?, G. N., Pérez-Quintanilla, D., ?i?ak, ?,. Jurani?, Z. D. and Gómez-Ruiz, S (2010). Improvement of cytotoxicity of titanocene-functionalized mesoporous materials by the increase of the titanium content. Dalton Trans. 2597–2608.
• Kalu?erovi?, G. N., Kommera, H., Hey-Hawkins, E., Paschke, R. and Gómez-Ruiz, S. (2010). Synthesis and biological applications of ionic triphenyltin(IV) chloride carboxylate complexes with exceptionally high cytotoxicity, Metallomics 2, 419–428.
• Pérez-Quintanilla, D., Gómez-Ruiz, S., ?i?ak, ?,. Sierra, I., Prashar, S., Hierro, I. Fajardo, M., Jurani?, Z. D. and Kalu?erovi?, G. N. (2009). A new generation of anticancer drugs. Mesoporous materials modified with titanocene complexes. Chem. – Europ. J. 22, 5588–5597.
• Kalu?erovi?, G. N., Kommera, H., Schwieger, S., Schmidt, H., Paethanom, A., Kunze, M., Paschke, R. and Steinborn, D. (2009). Preparation, DFT calculations and antitumoral investigations of some platinum(IV) complexes with O,O’-dialkyl-ethylenediamine-N,N’-di-3-propanoate (R2eddp) ligands, Dalton Trans. 10720–10726.

Reviews

• Kalu?erovi?, G. N., Paschke, R. (2011). Anticancer metallotherapeutics in preclinical Development, Curr. Med. Chem. 18, 4738–4752.
• Gómez-Ruiz, S., Maksimovi?-Ivani?, D., Mijatovi?, S., Kalu?erovi?, G. N. (2012). On the discovery, mechanism and use of cisplatin and metallocenes in anticancer chemotherapy, Bioinorg. Chem. Appl. Article ID 140284, 1–14.
• Kne?evi?, N. ?., Kalu?erovi?, G. N. (2017). Silicon-based nanotheranostics, Nanoscale 9, 12821–12829.
• Mijatovi? S., Bramanti A., Nicoletti, F., Faragone, P., Kalu?erovi?, G. N., Maksimovi?-Ivani?, D. (2018). Naturally occuring compounds in differentiation based therapy of cancer, Biotechnol. Adv. 36, 1622–1632.
• Zmejkovski, B.B., Panteli?, N.?., Kalu?erovi?, G.N. (2022): Palladium (II) complexes: Structure, development and cytotoxicity from cisplatin analogues to chelating ligands with N stereocenters, Inorg. Chim. Acta 120797.

Buchkapitel

• Kalu?erovi?, G. N., Schmidt, H., Steinborn, D., Sabo, T. J. (2008). Inorganic Biochemistry: Research Progress. In J. G. Hughes, A. J. Robinson, (Ed.), From synthesis to antitumoral activity of platinum(II) and platinum(IV) complexes with bis(carboxyalkylamino)ethane and -propane ligands (S. 305–326). NY: Nova Science Publishers, Inc. Hauppauge. ISBN: 978-1-60456-708-3.
• Wessjohann, L. A., Kalu?erovi?, G. N., Neves Filho, R. A. W. et al. (2013). Science of Synthesis: Multicomponent Reactions 1. In T. J. J. Müller (Ed.), Further Components Carboxylic Acid and Amine (Ugi Reaction) (S. 415–502). Stuttgart: Georg Thieme Verlag KG. ISBN: 9783131728616.
• Wessjohann, L. A., Schreckenbach, H. F., Kalu?erovi?, G. N. (2015). Science of Synthesis: Biocatalysis in Organic Synthesis 2. In K. Faber, W.-D. Fessner, N. J. Turner, N. J. (Eds.), Enzymatic C-Alkylation of Aromatic Compounds (S. 177–211). Stuttgart: Georg Thieme Verlag KG. ISBN: 9783131741417.

Lebenslauf

1994-1999 Chemiestudium, Fakult?t für Chemie, Universit?t Belgrad, Belgrad, Jugoslawien

2002 Magister, Fakult?t für Chemie, Universit?t Belgrad, Belgrad, Serbien und

2005 Dissertation, Fakult?t für Chemie, Universit?t Belgrad, Belgrad, Serbien undMontenegro

2006–2008 Alexander von Humboldt–Stipendiat bei Prof. Dr. D. Steinborn, Institut für Chemie, Martin-Luther-Universit?t Halle-Wittenberg, Deutschland

05/2014 Habilitation, Naturwissenschaftliche Fakult?t II - Chemie, Physik und Mathematik, Martin-Luther-Universit?t Halle-Wittenberg, Deutschland

Auszeichnungen
2007 Forschungspreis der Martin-Luckner-Stiftung für Entwicklung neuer Antitumorwirkstoffe
2008 Medaille der Serbischen Chemischen Gesellschaft für herausragende Leistungen und Erfolge in der Wissenschaft im Jahr 2008